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Respiration and Gaseous Exchange MCQs

Respiration MCQs are multiple-choice questions on the human respiratory system, covering the air passages, the mechanism of breathing, gas exchange in the alveoli, transport of gases in the blood and the effects of smoking. Every question on MCQs360 shows the correct answer instantly, so you can check your answers while you revise.

Compared with adult haemoglobin, where does the oxygen dissociation curve of fetal haemoglobin lie?

Correct answer A. To the left, because fetal haemoglobin has a higher affinity for oxygen

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Myoglobin in muscle releases its oxygen only when partial pressure of oxygen becomes very low. What does this show?

Correct answer A. Myoglobin has a higher affinity for oxygen than haemoglobin

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Why does oxygen move from the alveoli into the blood of pulmonary capillaries?

Correct answer C. The partial pressure of oxygen in alveolar air is higher than in the blood

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Why is the oxygen dissociation curve of haemoglobin S-shaped (sigmoid)?

Correct answer B. Binding of one oxygen molecule makes it easier for the next ones to bind

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Which sequence shows the correct path of inhaled air?

Correct answer C. Nasal cavity → pharynx → larynx → trachea → bronchi → bronchioles → alveoli

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About Respiration and Gaseous Exchange MCQs

Questions trace the path of air through the nasal cavity, pharynx, larynx, trachea, bronchi, bronchioles and alveoli, asking about the role of each part, the epiglottis, cartilage rings and ciliated epithelium. Breathing questions cover the action of the diaphragm and intercostal muscles, lung volumes and capacities, and the control of breathing by carbon dioxide levels. Gas exchange questions examine the features of alveoli, surfactant and diffusion. Transport questions cover haemoglobin, the oxygen dissociation curve, foetal haemoglobin, carbonic anhydrase and carbon monoxide poisoning. The final area deals with the effects of smoking, including chronic bronchitis, emphysema and lung cancer.

Key facts to remember

  • Gas exchange takes place across the thin walls of the alveoli by diffusion.
  • The trachea is kept open by C-shaped rings of cartilage.
  • During inspiration the diaphragm contracts and flattens and the external intercostal muscles raise the ribs.
  • Residual volume cannot be measured with a simple spirometer because it never leaves the lungs.
  • Carbon monoxide binds to haemoglobin far more strongly than oxygen, reducing the blood's oxygen-carrying capacity.
  • Most carbon dioxide is carried in the blood plasma as hydrogencarbonate (bicarbonate) ions.

Exams that include Respiration and Gaseous Exchange MCQs

Pakistan

  • MDCAT
  • NUMS
  • AKU
  • FSc boards

India

  • NEET

Bangladesh

  • HSC
  • Medical Admission Test

How to prepare for Respiration and Gaseous Exchange MCQs

  1. Draw and label the respiratory tract from the nose to the alveoli and note one function for each part.
  2. Practise lung volume calculations, remembering that vital capacity equals tidal volume plus both reserve volumes.
  3. Sketch the oxygen dissociation curve and show how it shifts with more carbon dioxide and for foetal haemoglobin.
  4. Make a list of the effects of smoking, matching each substance in smoke to the damage it causes.

Frequently asked questions

Which exams ask Respiration MCQs?

In Pakistan, Respiration questions appear in MDCAT, the NUMS and AKU entry tests and FSc board papers. Students in India meet the same content in NEET, and in Bangladesh it is tested in HSC Biology and the Medical Admission Test.

How does smoking damage the respiratory system?

Tar in smoke paralyses and destroys cilia and increases mucus, causing smoker's cough and chronic bronchitis. Damage to alveolar walls leads to emphysema, carcinogens in tar can cause lung cancer, and carbon monoxide reduces how much oxygen the blood can carry.

Why are alveoli efficient at gas exchange?

Alveoli provide a huge surface area, have walls only one cell thick, are moist and are surrounded by a dense network of capillaries. Continuous blood flow and ventilation keep steep concentration gradients of oxygen and carbon dioxide, so diffusion is rapid.

Last reviewed October 2026