Practice mode Immunity

Haemolytic disease of the newborn can occur when which situation arises?

Correct answer A. An Rh-negative mother carries an Rh-positive fetus after earlier sensitisation

Explanation

An Rh-negative mother sensitised by Rh-positive fetal cells makes anti-D IgG. In a later Rh-positive pregnancy these antibodies cross the placenta and destroy fetal red cells.

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